His commercial clients include Apple, IBM, Goldman Sachs, Chevron, Emirates Airlines & Forbes… Menuez’s work has been praised by industry and peers alike with honorable mentions and awards via The Cannes Festival, The Epson Creativity Award and the international photography awards. His photographs evoke a wide spectrum of emotions with more than 30 years of creating art through his documentation of cultures worldwide.ĭoug’s commissions range from Hollywood faces such as Charlize Theron and Robert Redford to Mother Teresa and Presidents Clinton and Bush Sr. The result is an unforgettable exhibition of photos that will be studied by generations to follow.ĭoug Menuez is a craftsman of human observance. Doug’s eye highlights the fortitude of what is achievable when a group of individuals share a collective mission. From the creators of the smartphone to the visionaries behind making the internet accessible to everyone, this era altered the course of humanity’s evolution.ĭoug’s anthropological study fostered a profound understanding into the daunting, magical, and excessive human beings who were critical in altering our perceptions of reality through the development of their tech dreams. With exclusive access to Steve Jobs, during a time described as the ‘golden era’ of Silicon Valley, Doug’s collection of masterfully crafted images documented a niche of American entrepreneurs who were on a mission to change the world. Notable influencers featured in Fearless Genius include: Bill Gates, Steve Jobs, David Hockey, Bill Clinton, John Sculley, Ross Perot, Susan Kare, Russel Brown, Bill JoyĬhelsea, NYC – HG Contemporary presents: Fearless Genius, a monumental photo exhibit showcasing a pivotal time in American & technological history. Opening Reception: March 8th 2018 Hours: 6-9:00 p.m. These findings suggest that free-radical-mediated vasogenic edema is not an important pathophysiological event that contributes to the mild brain swelling observed in HAH.A MONUMENTAL PHOTO EXHIBIT SHOWCASING THOSE WHO ALTERED THE COURSE OF HUMANITY’S EVOLUTION FOREVER A greater increase in brain volume was observed, though this was slight, independent of oxidative stress, barrier dysfunction, raised lumbar pressure, vascular damage and measurable evidence of cerebral edema and only apparent in the most severe of cases. Clinical AMS was diagnosed in 50% of subjects during the hypoxic trial and corresponding headache scores were markedly elevated (P<0.05 versus non-AMS). However, there was no detectable evidence for gross barrier dysfunction, elevated lumbar pressures, T2 prolongation or associated neuronal and astroglial damage. Magnetic resonance imaging (MRI) demonstrated a mild increase in brain volume (7.0+/-4.8 mL or 0.6%+/-0.4%, P<0.05 versus normoxia) that resolved within 6 h of normoxic recovery. Electron paramagnetic resonance (EPR) spectroscopy identified a clear increase in the blood and CSF concentration of O2 and carbon-centered free radicals (P<0.05 versus normoxia) subsequently identified as lipid-derived alkoxyl (LO*) and alkyl (LC*) species. ![]() ![]() Twenty-two subjects were randomly exposed for 18 h to 12% (hypoxia) and 21% oxygen (O2 (normoxia)) for collection of venous blood (0 h, 8 h, 15 h, 18 h) and CSF (18 h) after lumbar puncture (LP). The present study combined molecular and neuroimaging techniques to examine if free radical-mediated damage to barrier function in hypoxia would result in extracellular edema, raise intracranial pressure (ICP) and account for the neurological symptoms typical of high-altitude headache (HAH) also known as acute mountain sickness (AMS).
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